Ephedrine for Reducing Onset Time of Rocurinium in Elderly Patients
ConditionNeuromuscular Blockade
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age80+
SponsorMatias Vested
About this trial
The aim of this study is to determine the onset time of rocuronium after administration of ephedrine 0.15 mg/kg in patients with age ≥ 80 years. The hypothesis of this study is that ephedrine 0.15 mg/kg provides a shorter onset time compared to placebo (saline).
Eligibility criteria
Qualifiers
Age ≥ 80
Scheduled for elective operations under general anesthesia with intubation
American Society of Anesthesiologists physical status classification (ASA) I to III
Informed consent
Disqualifiers
Known allergy to rocuronium or ephedrine
Neuromuscular disease that may interfere with neuromuscular data
Indication for rapid sequence induction
Daily use of beta-blocking agents
Trial design
Treatments tested in this trial
- Ephedrine Hydrochloride 30 mg/ml
- Saline (NaCl 0,9 %) (placebo)
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Matias Vested
Lead sponsor
Rigshospitalet, Denmark
Sponsor institution
Source ClinicalTrials.gov