Hemodynamics During Cesarean Delivery Under Spinal Anesthesia With Norepinephrine Versus Ephedrine
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age19-40
SponsorMansoura University
About this trial
Echocardiography will be used to measure cardiac output and calculate other important hemodynamic variables in healthy patients with full-term singleton pregnancy during cesarean delivery under conventional spinal anesthesia using 2 different vasopressor drugs: norepinephrine in 1 group versus ephedrine in another group.
Eligibility criteria
Qualifiers
American Society of Anesthesiologists physical status II.
Singleton, full term pregnancy.
Scheduled cesarean delivery under spinal anesthesia.
Disqualifiers
Height <150 or >180 cm.
Weight <60 or >110 kg.
Body mass index (BMI) <18.5 or ≥35 kg/m².
Women presenting in labor.
Trial design
Treatments tested in this trial
- Spinal Anesthesia with Bupivacaine and Fentanyl
- Crystalloid Coload 1000 mL
- Cesarean Delivery
- Transthoracic Echocardiography
- Intravenous Norepinephrine Bolus
- Intravenous Ephedrine Bolus
Treatment groups
200 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov