This is a multicentre prospective, randomized, double-blind and imitation, positive-drug parallel controlled clinical trail. The objective of this study is to evaluate the efficacy and safety of Huaiqihuang Granule in patients with CKD stage 3 primary glomerulonephritis.
Diagnosed as primary glomerulonephritis by renal biopsy
Male or female, 18≤age≤65
Blood pressure can be effectively controlled at or below 140/90mmHg
30mL/（min.1.73m2）≤ eGFR<60mL/（min.1.73m2）
Diagnosed as secondary glomerulonephritis
Exposure to corticosteroids, immunosuppressors, tripterygium glycosides, ARBs or ACEIs, without a two weeks washout period
Blood pressure < 90/60 mmHg
Serum potassium > 5.5 mmol/L
The First Affiliated Hospital of Dalian Medical University
Lead sponsor
Huazhong University of Science and Technology
Collaborator
LinkDoc Technology (Beijing) Co. Ltd.
Collaborator