The purpose of this study is to determine whether ICD(Implantable Cardioverter Defibrillator) implantation on the top of optimal medical therapy in patients with variant angina manifesting as aborted sudden cardiac death reduces the incidence of the death from any cause compared with optimal medical therapy alone.
Age 18 years or older
Patients experienced successfully resuscitated cardiac arrest due to documented ventricular fibrillation or sustained rapid ventricular tachycardia
Diagnosed as variant angina, defined by spontaneous coronary spasm with ST elevation (≥0.1mV) in the coronary angiogram and/or documented coronary spasm on ergonovine provocation coronary angiography
Significant (>50%) coronary artery stenosis on coronary angiography
Organic heart disease known to be associated with sudden cardiac arrest.
Heart failure with reduced ejection fraction (Left Ventricular Ejection Fraction < 35%)
Presence of LV akinesia or aneurysm
Kee-joon Choi
Lead sponsor
Asan Medical Center
Sponsor institution
CardioVascular Research Foundation, Korea
Collaborator