The CRITICal study aims to estimate the effectiveness of intermittent preventive treatment in school children (IPTsc) with dihydroartemisinin-piperaquine (DP) for reducing community level malaria burden. Given that school-aged children are the primary drivers of transmission, the study hypothesis is that IPTsc will reduce this infectious reservoir and thus the burden of malaria in persons of all ages in surrounding communities.
Child currently attending the participating school.
Agreement of parent/guardian to provide informed consent.
Agreement of children aged 8-17 years to provide assent.
Missing school on three consecutive days of the school survey.
University of California, San Francisco
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator
Infectious Diseases Research Collaboration, Uganda
Collaborator
Ministry of Health, Uganda
Collaborator