Intranasal Nafarelin For Triggering Oocyte Maturation
ConditionFertility Preservation
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18-40
SponsorFundacion Dexeus
About this trial
This is a non-inferiority randomised, controlled clinical trial comparing subcutaneous triptorelin to intranasal nafarelin for the final maturation of oocytes in women undergoing fertility preservation cycles with oocyte cryopreservation undergoing ovarian stimulation.
Eligibility criteria
Qualifiers
Women undergoing fertility preservation cycles with oocyte cryopreservation
Undergoing a progesterone-primed ovarian stimulation cycle (PPOS) with any commercially available gonadotropin preparation(s)
BMI 18 - 30 kg/m2
Disqualifiers
Allergy or hypersensitivity to either of the study drugs
Hypopituitarism
Known pituitary tumour
Contraindication to intranasal medication administration
Trial design
Treatments tested in this trial
- Subcutaneous Triptorelin
- Intranasal nafarelin
Treatment groups
154 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov