Double blind, double dummy trial of the use of IV acetaminophen versus oral acetaminophen for the prevention of delirium after cardiac surgery. The underlying hypothesis is that better pain control and less use of narcotics will lead to a lower incidence of delirium from day 1 to 7 following cardiac surgery. Other important secondary outcomes are the total use of narcotics, ICU and hospital stay, improved cognitive function at 6 months and 1 year post surgery, NSAID use at each centre and associated NSAID complications.
elective cardiac surgery
stable pre-operative
aorto-coronary bypass with or without 1 valve replacement.
None
McGill University Health Centre/Research Institute of the McGill University Health Centre
Lead sponsor
Laval University
Collaborator
University of British Columbia
Collaborator
St. Boniface Hospital
Collaborator
University of Ottawa
Collaborator
Trillium Health Centre
Collaborator
Université de Montréal
Collaborator
Sunnybrook Health Sciences Centre
Collaborator