Investigating the Optimal Remifentanil and Dexmedetomidine Concentration for Uterine Fibroid Ablation

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age20-65
SponsorKaohsiung Medical University

About this trial

This clinical trial aims to find a better drug concentration of Remifentanil in Uterine Fibroid Ablation. The main question it seeks to answer is:

\[primary hypothesis 1\] Remifentanil concentration of 2.0 ng/mL provides better pain control in Uterine Fibroid Ablation.

There is a comparison group in this study: Researchers will compare Remifentanil concentration of 1.0 ng/mL to see if provides similar pain control with fewer side effects.

Participants will be separated into two groups, one group with a Remifentanil concentration of 2.0 ng/mL and the other 1.0 ng/mL. During uterine fibroid ablation, the patient\'s pain index will be recorded (using a Visual Analogue Scale (VAS) of 0\~10 points). We will also record vital signs during the procedure.

Eligibility criteria

Qualifiers

Aged between 20 and 65 years old

American Society of Anesthesiology classification I~III

Female patients diagnosed with uterine fibroids by obstetricians and gynecologists

Disqualifiers

Patients with heart disease (such as arrhythmia or severe ventricular dysfunction)

Patients with chronic kidney disease in stage III or above or dialysis patients

Long-term alcohol addiction or drug abuse

Patients with abnormal liver index or chronic hepatitis

Trial design

Treatments tested in this trial

  • arm 2
  • arm 1

Treatment groups

60 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators