Lactated Ringer's and Dextrose 5% vs Only Lactated Ringer's in Labor

ConditionInduced Labor
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18+
SponsorEastern Virginia Medical School

About this trial

The goal of this clinical trial is to determine which of two types of standard intravenous (IV) fluids (a combination of 5% dextrose and Lactated Ringers solution and Lactated Ringers solution alone) has a better influence on labor when inducing labor in pregnant women. The main questions it aims to answer are:

1. Does the use of 5% dextrose and Lactated Ringers lead to a shorter labor than the use of just Lactated Ringers? 2. Does the use of 5% dextrose and Lactated Ringers increase the risk of neonatal hypoglycemia when compared to Lactated Ringers? Participants in this trial will be randomly assigned to one of two groups: a group that receives a solution of 5% dextrose and Lactated Ringers, and a group that receives Lactated Ringers alone. Researchers will compare the outcomes of the two groups to see which IV fluid is more effective.

Eligibility criteria

Qualifiers

Nulliparous women

Age 18 years or older and able to provide informed consent

Singleton pregnancy at term

Induction of labor

Disqualifiers

Age under 18 years

Involuntarily confined or detained

Considered as having diminished decision-making capacity

Spontaneous labor (cervical exam between 5-6 cm) with or without ruptured membraned

Trial design

Treatments tested in this trial

  • 5% Dextrose (D5) in Normal Saline (NS)
  • Lactate Ringer

Treatment groups

158 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Eastern Virginia Medical School

Lead sponsor

University of Modena and Reggio Emilia

Collaborator