About this trial
The goal of this clinical trial is to determine which of two types of standard intravenous (IV) fluids (a combination of 5% dextrose and Lactated Ringers solution and Lactated Ringers solution alone) has a better influence on labor when inducing labor in pregnant women. The main questions it aims to answer are:
1. Does the use of 5% dextrose and Lactated Ringers lead to a shorter labor than the use of just Lactated Ringers? 2. Does the use of 5% dextrose and Lactated Ringers increase the risk of neonatal hypoglycemia when compared to Lactated Ringers? Participants in this trial will be randomly assigned to one of two groups: a group that receives a solution of 5% dextrose and Lactated Ringers, and a group that receives Lactated Ringers alone. Researchers will compare the outcomes of the two groups to see which IV fluid is more effective.
Eligibility criteria
Qualifiers
Nulliparous women
Age 18 years or older and able to provide informed consent
Singleton pregnancy at term
Induction of labor
Disqualifiers
Age under 18 years
Involuntarily confined or detained
Considered as having diminished decision-making capacity
Spontaneous labor (cervical exam between 5-6 cm) with or without ruptured membraned
Trial design
Treatments tested in this trial
- 5% Dextrose (D5) in Normal Saline (NS)
- Lactate Ringer
Treatment groups
Sponsors and collaborators
Eastern Virginia Medical School
Lead sponsor
University of Modena and Reggio Emilia
Collaborator