LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age65+
SponsorYale University
About this trial
To establish the effectiveness and tolerability of standard of care anti-anginal treatment (beta-blocker and calcium channel blocker medications) in older adults with symptomatic Stable Ischemic Heart Disease (SIHD) and multiple chronic conditions (MCC).
Eligibility criteria
Qualifiers
Age ≥65 years
≥ 2 Multiple Chronic Conditions as defined by Centers for Medicare and Medicaid Services (CMS)
positive non-invasive functional or anatomic testing suggestive of obstructive coronary artery disease
coronary angiography with stenosis ≥70% in a coronary artery ≥2 mm in diameter or
Disqualifiers
Current taking (both) a beta-blocker AND a calcium channel blocker*
significant hypotension
high grade AV block
severe symptomatic bradycardia
Trial design
Treatments tested in this trial
- Clinician Discretion
- Beta blocker
- Calcium channel blocker
Treatment groups
741 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov