Mass Vaccine and Drug Administration, Bangladesh
ConditionPlasmodium Falciparum Malaria
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age6+
SponsorUniversity of Oxford
About this trial
This is an open i.e. not blinded, cluster-randomised, controlled intervention study. The study will use a factorial design to estimate the protective effectiveness of mass drug administrations, mass vaccinations, combined mass vaccinations and drug administrations versus the current standard of care.
Eligibility criteria
Qualifiers
Current residence in a study village irrespective of permanence
Age 6 months and above (no upper age limit)
Written informed consent provided by participants (or a parent/guardian in case the participant is under 18 years old)
Disqualifiers
Pregnancy, plan to get pregnant, or breastfeeding.
Acute illness requiring intervention
A history of an adverse reaction to study drugs/vaccine and prior receipt of any other malaria vaccine or enrolment in another intervention trial.
Trial design
Treatments tested in this trial
- DHA/piperaquine and a SLD-PQ
- Study vaccine R21/Matrix-M™
Treatment groups
10,000 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov