NextGen - Clinical Implication of Next Generation Sequencing
ConditionUrinary Tract Infections
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18-80
SponsorWake Forest University Health Sciences
About this trial
Recently more advanced techniques, including Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) are available to detect bacteria in urine based on bacterial genomes. Comparing to traditional culture, these techniques have more sensitivity and could potentially be of a great help in patients with Colony Count of less than 10,000 and more than zero.
Eligibility criteria
Qualifiers
Female at least 18 years of age
U/C (Urinary Culture) growth of <10,000 Colony-Forming Units (CFU)
Understanding and acceptance of the need to return for all scheduled follow-up visits
Able to give informed consent
Disqualifiers
Catheter in use (Foley or suprapubic or intermittent)
Not able to provide clean midstream urine
Antibiotic consumption in the past 2 weeks before signing the consent
Pregnant or Planning to Conceive
Trial design
Treatments tested in this trial
- Antibiotic
- Next Gen
Treatment groups
100 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov