NICardipine for Fast Achievement of Systolic BP Targets in ICH
ConditionIntracerebral Haemorrhage
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorAarhus University Hospital
About this trial
Quality improvement study with a quasi-randomized design. The study monitors the effect of a gradually implemented treatment algorithm prioritizing intravenous antihypertensives (e.g., nicardipine) over long-acting nitrate patches. It aims to increase the proportion of patients reaching target systolic BP \<140 mmHg within 1 hour of hospital admission while monitoring safety, clinical outcomes, and healthcare resource utilization.
Eligibility criteria
Qualifiers
Age ≥18 years
Acute spontaneous Intracerberal Hemorrhage confirmed by imaging
Symptom onset to stroke center admission <6 hours
Elevated systolic blood pressure (>140 mmHg) at admission
Disqualifiers
Secondary causes of ICH (e.g., trauma, vascular malformation)
Presumed fatal bleeding at admission
Short remaining life expectancy (<12 month)
Trial design
Treatments tested in this trial
- Nicardipine
- Glyceryl trinitrate
Treatment groups
88 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov