Once Weekly Infant Corticosteroid Trial for DMD
ConditionDuchenne Muscular Dystrophy
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexMale
Age1-30
SponsorAnne M. Connolly
About this trial
The hypothesis tested here is that a lower dose of intermittent oral corticosteroids (5mg/kg/week) will be equally effective to the 10mg/kg/week dose.
Eligibility criteria
Qualifiers
Subjects ages 1 month through 30 months
Weakness consistent with Duchenne on exam, creatine kinase ≥ 20 times the upper limit of normal, and genetic mutation known to be causative for DMD.
Disqualifiers
Prior treatment with Glucocorticosteroids
Trial design
Treatments tested in this trial
- Prednisolone
Treatment groups
26 Participants
are divided into 1 treatment groupSponsors and collaborators
Anne M. Connolly
Lead sponsor
Nationwide Children's Hospital
Sponsor institution
Children's Hospital Medical Center, Cincinnati
Collaborator
Muscular Dystrophy Association
Collaborator
University of Texas
Collaborator
Virginia Commonwealth University
Collaborator
Ann & Robert H Lurie Children's Hospital of Chicago
Collaborator
Source ClinicalTrials.gov