Optimal Intravesical Lidocaine Volume for Pain Relief During Office Intra-detrusor Onabotulinum Toxin a Injections

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18+
SponsorUniversity of Louisville

About this trial

The purpose of our study is to evaluate the efficacy and safety of different volumes of bladder-numbing medication for pain relief at the time of office bladder Botox injections. This is a randomized prospective, double-blind superiority trial comparing 200 ml 2% lidocaine versus 30 ml 2% lidocaine for office Botox injections.

Eligibility criteria

Qualifiers

Adult female, >18 years, English-speaking (surveys utilized are not validated in all languages)

Able to provide informed consent

Indications: Refractory urge urinary incontinence, Refractory urinary urgency and frequency, Neurogenic bladder (without sensory deficit)

Disqualifiers

Untreated urinary tract infection at the time of procedure

Contra-indication to Botox

Contraindication to intravesical lidocaine

Inability to provide informed consent

Trial design

Treatments tested in this trial

  • Lidocaine 2% without vessel constrictor

Treatment groups

36 Participants
are divided into 2 treatment groups

Sponsors and collaborators