Optimize Immunosuppressive Therapy Using Everolimus and Low-dose Calcineurin Inhibitors in Heart Transplant Patients in Korea

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age19+
SponsorChong Kun Dang Pharmaceutical

About this trial

The purpose of this study is to evaluate the efficacy and safety of lower dose calcineurin inhibitors (CNI) in combination with Everolimus in Korean heart transplant recipients.

Eligibility criteria

Qualifiers

Over 19 years old

Patients with stable heart transplant graft function at least 28~100 days post transplant.

Patients who are appropriate for combination therapy with Everolimus and Calcineurin inhibitor (CNI) at the investigator's discretion

Disqualifiers

Recipients who have had a prior organ transplant, or who underwent a heart transplant with the simultaneous transplantation of another organ.

Recipients of heart from ABO-incompatible donor

Recipients of heart from the donor aged 70 or older

Trial design

Treatments tested in this trial

  • Everolimus
  • Mycophenolate mofetil Tablet/Capsule

Treatment groups

140 Participants
are divided into 2 treatment groups

Sponsors and collaborators