Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18+
SponsorUniversity of North Carolina, Chapel Hill

About this trial

The goal of the study to see if giving a numbing medicine around the cervix (called a paracervical block) during vaginal hysterectomy with prolapse repair helps people feel less pain and need fewer strong pain medicines afterward.

The main question it aims to answer is:

• Does receiving a paracervical block at the time of vaginal hysterectomy with prolapse repair reduce postoperative opioid use?

Researchers will compare opioid use in participants who receive the an injected numbing medicine (bupivacaine with lidocaine) to those that receive a saltwater liquid placebo.

Participants will:

* Receive either an injection of the numbing medicine (bupivacaine with lidocaine) or saltwater liquid placebo after they are asleep but before any other parts of the surgery are done * Record and report pain medications used for 7 days after surgery * Report pain scores before discharge from the post anesthesia recovery area on day of surgery as well as 1 and 7 days after surgery * Complete a surgical recovery questionnaire during 6 week postoperative visit * Complete a one page multiple-choice test on pelvic organ prolapse

Eligibility criteria

Qualifiers

Individuals undergoing vaginal hysterectomy with concomitant prolapse repair procedure

Disqualifiers

Non-English speaking

Weight less than 50 kg

Allergy to bupivacaine

Pregnant

Trial design

Treatments tested in this trial

  • Bupivacaine-epinephrine
  • Normal saline

Treatment groups

56 Participants
are divided into 2 treatment groups