About this trial
The purpose of this study is to find out if IV lidocaine infusion decreases the need of opioids, improves pain management, and reduces the risks of developing complications from prolonged opioid use in burn injury participants undergoing wound debridement in the operating room.
Participants will:
* be randomized to receive either an IV Lidocaine treatment or an IV Saline Placebo during their surgery. The IV treatment continues for 48 hours after surgery. * be asked about their pain and how they're feeling at 4 timepoints during the 48 hours. * be asked about their pain 2 weeks after surgery.
The participant and medical care providers will both be blinded to what IV treatment is being received.
Researchers will compare the 2 groups to see if IV Lidocaine helps decrease the need of opioids, improves pain management, and reduces the risks of developing complications from prolonged opioid use (this includes opioid tolerance, opioid dependence, and opioid induced hyper-sensitivity to pain).
Eligibility criteria
Qualifiers
Acute burn patients
18 years or older
<20% Total Body Surface Area
Wound debridement surgery scheduled at Harborview Medical Center
Disqualifiers
History of polysubstance use
Chronic opioid use (MED>40mg for more than 6 weeks)
Cases where the known clinical standard care would be to keep patient intubated postoperatively
Cases where the known clinical standard care would avoid IV Lidocaine infusion
Trial design
Treatments tested in this trial
- IV Lidocaine
- IV Saline