About this trial
Currently, in clinical practice there has been no standardization in the number of injections a single dose of intradetrusor onabotulinumtoxin A is administered in. Given the increasing use of this treatment modality, the aim of this study is to compare outcomes for patients given a 100 unit dose of onabotulinumtoxin A split into 5 as compared to 20 injections for the treatment of overactive bladder or urgency urinary incontinence refractory to medical treatment.
Eligibility criteria
Qualifiers
Women >=18 years of age with diagnosis of urinary urgency, urinary frequency, urgency urinary incontinence, overactive bladder.
Procedure scheduled in either the outpatient clinic or the operating room to be performed without use of sedation, general, or neuraxial anesthesia.
Disqualifiers
Male gender.
Women <18 years of age.
Non-English speaking.
Pregnancy (patient will self-report pregnancy).
Trial design
Treatments tested in this trial
- OnabotulinumtoxinA 100 UNT
Treatment groups
Sponsors and collaborators
University of South Florida
Lead sponsor
Medstar Health Research Institute
Collaborator