Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18+
SponsorUniversity of South Florida

About this trial

Currently, in clinical practice there has been no standardization in the number of injections a single dose of intradetrusor onabotulinumtoxin A is administered in. Given the increasing use of this treatment modality, the aim of this study is to compare outcomes for patients given a 100 unit dose of onabotulinumtoxin A split into 5 as compared to 20 injections for the treatment of overactive bladder or urgency urinary incontinence refractory to medical treatment.

Eligibility criteria

Qualifiers

Women >=18 years of age with diagnosis of urinary urgency, urinary frequency, urgency urinary incontinence, overactive bladder.

Procedure scheduled in either the outpatient clinic or the operating room to be performed without use of sedation, general, or neuraxial anesthesia.

Disqualifiers

Male gender.

Women <18 years of age.

Non-English speaking.

Pregnancy (patient will self-report pregnancy).

Trial design

Treatments tested in this trial

  • OnabotulinumtoxinA 100 UNT

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of South Florida

Lead sponsor

Medstar Health Research Institute

Collaborator