Postoperative Oral Tranexamic Acid in Patients Undergoing Primary Total Joint Arthroplasty
ConditionArthroplasty
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorMayo Clinic
About this trial
The purpose of this study is to evaluate the impact of an extended oral Tranexamic Acid regimen on patient reported outcome scores, time to independent ambulation, postoperative range of motion, swelling, change in hemoglobin levels, 90-day complications, readmission and reoperation.
Eligibility criteria
Qualifiers
Adults aged > 18 years (All women of childbearing potential undergo pregnancy testing prior to THA as per our institutional protocol)
Written informed consent
Patients undergoing primary THA diagnosis of end-stage osteoarthritis
Patients receiving spinal anesthesia
Disqualifiers
Patients with a TXA allergy
Patients undergoing revision procedures
Patients undergoing primary THA for a diagnosis other than end-stage osteoarthritis
Patients receiving general anesthesia
Trial design
Treatments tested in this trial
- Oral Tranexamic Acid
Treatment groups
101 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov