Protocol with Progestin-primed Ovarian Stimulation (PPOS) from the Beginning of Stimulation Versus Protocol with GnRH Antagonists for Ovarian Stimulation in Patients Undergoing DUOSTIM with Embryo Accumulation for PGT-A.

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18-43
SponsorGinefiv

About this trial

The PPOS protocol (Progestin-primed Ovarian Stimulation) involves avoiding ovulation during ovarian stimulation with progesterone. It is a reliable and safe protocol that has been widely used in recent years for in vitro fertilization, as it reduces the number of injections needed during controlled ovarian stimulation and is more cost-effective for patients.

The aim of this study is to compare two methods of ovarian stimulation for in vitro fertilization: the PPOS protocol (Group A) and the conventional protocol with injected antagonists (Group B). The goal is to determine whether both methods are equally effective in obtaining euploid embryos in the context of double ovarian stimulation.

Eligibility criteria

Qualifiers

Regular menstrual cycles between 21 and 35 days, inclusive.

Indication of IVF with PGT-A.

Both ovaries present.

Ability to participate and complete the study.

Disqualifiers

Endometriosis grade III/IV

Concurrent participation in another study

Trial design

Treatments tested in this trial

  • Ganirelix
  • Medroxyprogesterone Acetate 10 MG

Treatment groups

144 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Ginefiv

Lead sponsor

Theramex

Collaborator