Randomized Controlled Study to Compare Efficacy of Aspirin 75mg and 150mg In the Prevention of Preeclampsia In High Risk Pregnant Women

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18+
SponsorDr. Sunita Pun

About this trial

Preeclampsia in pregnancy is a dreaded complication which has both fetal and maternal adverse outcomes. Studies and WHO have advocated that this complication can be prevented by Aspirin. However which dose is more effective in preventing preeclampsia, whether 75mg or 150mg, will be known from this study.

Eligibility criteria

Qualifiers

• All pregnant women with Gestosis score of 3 or more who consents for the study and aged 18 years and above.

Disqualifiers

• Known hypersensitivity to aspirin, uncontrolled asthma with NSAID sensitivity

Bleeding disorders, platelet dysfunction, thrombocytopenia, anticoagulant use, active peptic ulcer, history of GI bleed, severe hepatic/ renal disease

Trial design

Treatments tested in this trial

  • Aspirin

Treatment groups

86 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Dr. Sunita Pun

Lead sponsor

Tribhuvan University, Nepal

Sponsor institution