Remimazolam and Emergence Delirium in Pediatrics
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age1-6
SponsorPeking University First Hospital
About this trial
Emergence delirium is a common complication in pediatrics undergoing neurosurgery. Previous study showed that a single bolus of remimazolam was associated with lower incidence of postoperative agitation. Present study was designed to investigate if remimazolam supplemented to sevoflurane anesthesia could decrease the risk of emergence delirium in pediatrics undergoing neurosurgery.
Eligibility criteria
Qualifiers
Aged 1 to 6 years old
Planned to receive elective neurosurgery under general anesthesia
Expected duration of surgery > 1 hour
Disqualifiers
Allergy to benzodiazepine
Use of other sedatives within 12 hours before surgery such as benzodiazepines, propofol, chloral hydrate, etc.,
ASA classification IV or above
Unable to complete emergence delirium assessment, such as language, hearing or vision impairment.
Trial design
Treatments tested in this trial
- Remimazolam
- Normal Saline
Treatment groups
248 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov