SPARK Study - Sympathetic Periarterial Radial Block in Healthy Volunteers
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-50
SponsorDuke University
About this trial
The SPARK Study evaluates changes in peripheral sympathetic vasomotor activity following a targeted, ultrasound-guided periarterial sympathetic block of the distal radial artery in healthy volunteers. Autonomic reactivity will be assessed before and after the block using digit-specific pulse-amplitude index and infrared thermography during standardized cold pressor testing.
Eligibility criteria
Qualifiers
Age 18-50 years
ASA physical status I-II
Able to understand and provide informed consent
Able to comply with study procedures and follow-up
Disqualifiers
Allergy to lidocaine or similar anesthetics
Allergy to adhesives or ultrasound gel
Neuromuscular, autonomic, or major vascular disorders affecting upper extremities
Peripheral neuropathy
Trial design
Treatments tested in this trial
- Lidocaine 2%
Treatment groups
20 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov