Supplementary Kelulut Honey Therapy in Juvenile Open-Angle Glaucoma: Effects on IL-6, RNFL and Dry Eye

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age15-40
SponsorUniversiti Sains Malaysia

About this trial

The goal of this clinical trial is to evaluate the effects of stingless bee honey (Kelulut honey) in juvenile open-angle glaucoma patients. The study evaluates the effects on serum Interleukin 6 level(IL-6), retinal nerve fiber layer(RNFL) thickness and dry eye-related symptoms. A total of 60 participants who meet the study criteria will be randomly assigned to one of two groups. One group will consume 30 grams of Kelulut honey daily for a period of three months, while the control group will not receive honey or a placebo. Serum IL-6 level, RNFL thickness, Tear break up time (TBUT) and Schirmer Test 1 will be done before and after 90 days. Adherence to honey consumption will be monitored using a daily diary. This study aims to provide better understanding of the potential role of Kelulut honey as a supplementary therapy in patients with juvenile open-angle glaucoma.

Eligibility criteria

Qualifiers

None

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Stingless bee honey (Kelulut)

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Universiti Sains Malaysia

Lead sponsor

Hospital Universiti Sains Malaysia

Sponsor institution

Hospital Raja Perempuan Zainab II, Kota Bahru, Kelantan

Collaborator

Hospital Sultanah Nur Zahirah, Kuala Terengganu

Collaborator

Hospital Universiti Sains Malaysia

Collaborator