Suzetrigine Versus Usual-care Opioids for Postop Pain in Sports

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of California, Los Angeles

About this trial

The goal of this clinical trial is to learn if a Suzetrigine-based multimodal pain regimen can reduce the volume of opioid consumption while maintaining non-inferior pain control compared to an opioid-based multimodal pain regimen after common ambulatory orthopaedic sports procedures. The main questions it aims to answer are:

1. Does including Suzetrigine in the multimodal pain regimen lower the volume of opioids consumed by participants while maintaining non-inferior pain control? 2. How does the side-effect profile of a Suzetrigine-based multimodal postop pain regimen compare to that of an opioid-based multimodal postoperative pain regimen?

Eligible participants will be assigned to receive one of the postop pain regimens and report their opioid use, their pain level, and the side effects they faced every day for 7 days.

Eligibility criteria

Qualifiers

Patients undergoing reconstruction of primary ACL tear

Disqualifiers

Concurrent ligamentous injuries requiring surgical intervention

Full thickness cartilage injury requiring discrete surgical intervention

Chronic opioid use

Significant hepatic disease (Child/Pugh C)

Trial design

Treatments tested in this trial

  • Suzetrigine
  • Multimodal Pain Regimen

Treatment groups

140 Participants
are divided into 2 treatment groups

Locations

This trial has no locations