The Effect of Remimazolam Versus Propofol on Postoperative Extubation Time

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-80
SponsorXuyu Zhang

About this trial

This clinical trial aims to help us understand how two drugs, Propofol and Remazoloam, affect when researchers remove a Participants' breathing tube after liver surgery (laparoscopic liver resection).The main research questions include: comparing the time to breathing tube removal between patients who receive each drug, comparing changes in heart rate and blood pressure during surgery, and comparing the rates of unwanted medical events after surgery. Researchers will give either Propofol or Remimazolam as a sedative medicine for anesthesia. This will allow the researchers to compare the time to breathing tube removal after surgery. Participants will complete their surgery according to a pre-planned surgical plan.

Eligibility criteria

Qualifiers

1): Planned to undergo laparoscopic hepatectomy.

Disqualifiers

1): Severe cardiopulmonary dysfunction, or hepatic/renal dysfunction.

Trial design

Treatments tested in this trial

  • Remimazolam
  • propofol

Treatment groups

82 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Xuyu Zhang

Lead sponsor

First Affiliated Hospital, Sun Yat-Sen University

Sponsor institution