The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery

ConditionsKnee Arthroplasty, Total Knee Arthritis, Osteoarthritis Total Knee Anthroplasty Blood Loss Tranexamic Acid Use Epinephrine

Trial statusRecruiting

Trial phasePhase 4

Trial typeInterventional

Biological sexAll

Age18-70

SponsorKing Abdullah International Medical Research Center

About this trial

The aim of this clinical trial is to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative blood loss, thromboembolic complications, and hospitalization duration in patients undergoing knee joint arthroplasty.

Also aim to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative thromboembolic complications, and hospitalization duration

Eligibility criteria

Qualifiers

Patients undergoing knee joint arthroplasty.

Saudi and Non-Saudi Patient.

Patients who have Complete medical record.

Disqualifiers

End stage renal disease

Liver cirrhosis

Coagulopathy

Pre-operative Hgb <10 5.

Trial design

Treatments tested in this trial

low-dose epinephrine and tranexamic acid
Tranexamic Acid (TXA) treatment

Treatment groups

80 Participants

are divided into 2 treatment groups

Sponsors and collaborators

King Abdullah International Medical Research Center

Lead sponsor

Source ClinicalTrials.gov