THRIVE Study: Understanding How Oral Nicotine Pouches Affect Public Health

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age21+
SponsorOhio State University Comprehensive Cancer Center

About this trial

Although nicotine pouches have been gaining popularity over the last few years, little known about how nicotine pouch users actually use these products.

This study will be comprised of adults who use nicotine pouches. If eligible, participants will be asked to complete three study visits and participate in two switching periods where participants use study-provided nicotine pouches.

Eligibility criteria

Qualifiers

Age 21 or older

Able to read and speak English

Willing to abstain from tobacco, nicotine, and marijuana for at least 12 hours prior to study visits

Exclusive use of ONPs (other product use <10x/mo).

Disqualifiers

Non-English speaker

Individuals currently pregnant, planning to become pregnant, or breastfeeding are excluded due to potential risks associated with nicotine exposure and study procedures (e.g., blood draws).

Individuals with unstable or significant psychiatric conditions are excluded to minimize risk and ensure reliable participation.

Individuals actively attempting to quit nicotine use are excluded to avoid ethical concerns and ensure that study participation does not interfere with cessation efforts

Trial design

Treatments tested in this trial

  • Biospecimen Collection
  • Nicotine Oral Pouch
  • Nicotine Oral Pouch
  • Survey Administration
  • Text Message-Based Navigation Intervention

Treatment groups

15 Participants
are divided into 2 treatment groups