To Investigate the Effect of Esketamine Hydrochloride on Pulmonary Complications
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-75
SponsorZhang XIao Mei
About this trial
The objective of this study was to evaluate the effect of esketamine on intraoperative hemodynamics in patients with heart valve replacement and to mitigate postoperative pulmonary complications
Eligibility criteria
Qualifiers
Age 18-75 years old, gender unlimited.
Elective heart surgery.
Patients who plan to undergo mitral and (or) aortic valve replacement (or repair) surgery, requiring extracorporeal circulation and aortic occlusion.
The New York Heart Association class is less than 4.
Disqualifiers
Non-cardiac surgery.
Second heart surgery.
Interventional surgery in heart valve surgery (TAVI, mitral clamp).
The patient refuses.
Trial design
Treatments tested in this trial
- Esketamine hydrochloride injection
Treatment groups
102 Participants
are divided into 3 treatment groupsSponsors and collaborators
Zhang XIao Mei
Lead sponsor
Zunyi Medical College
Sponsor institution
Source ClinicalTrials.gov