About this trial
The goal of this study is to find out whether the use of topical tranexamic acid (TXA) into the surgical wound will result in less post-operative pain, less pain killer use, and better post-operative use of the wrist in people undergoing surgery for a wrist fracture compared to not using topical TXA (placebo).
Eligibility criteria
Qualifiers
Patients undergoing open reduction internal fixation (Volar approach) for operative management of a distal radius fracture;
Aged 18 or older;
Provision of informed consent;
Cognitive ability and English-language skills required to complete outcome measures.
Disqualifiers
Revision surgery or any additional operative management of ipsilateral wrist injury
Distal radius fracture treated with a dorsal approach
Known history of lymphedema or lymph node dissection in the operative extremity
Known chronic pain conditions, fibromyalgia, or polymyalgia rheumatic
Trial design
Treatments tested in this trial
- Topical TRanexamic Acid
- Placebo