TRAP Study: Testosterone for Androgen Receptor Polymorphism
ConditionFertility Disorders
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18-40
SponsorInstituto Bernabeu
About this trial
To determine whether pretreatment with transdermal testosterone increases the number of cumulus-oocyte complexes (COCs) obtained after ovarian stimulation by more than 1.5 in patients with low ovarian reserve and androgen receptor polymorphism undergoing intracytoplasmic sperm injection (ICSI).
Eligibility criteria
Qualifiers
Age equal to or greater than 40 years.
Previous cycle with less than 4 oocytes retrieved.
Low ovarian reserve markers (antral follicle count <5-7; AMH <0.5-1.1 ng).
Carriers of androgen receptor polymorphism: between 22 and 24 CAG repeats.
Disqualifiers
Non-compliance with instructions or non-formalization of informed consent.
Concurrent participation in another study.
Trial design
Treatments tested in this trial
- Transdermal Gel in Sachet Dosage Form
- No pretreatment
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov