Treatment With Indapamide in Patients With Post-Surgical Hypoparathyroidism
ConditionHypoparathyroidism Post-surgical
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorLars Rejnmark
About this trial
The aim of this study is to investigate the effect of daily treatment with Indapamide for 14 days on urinary calcium excretion in patients with post surgical hypoparathyroidisme.
Eligibility criteria
Qualifiers
Chronic post surgical hypoparathyroidism diagnosed > 1 year ago
Age ≥ 18 years
Require treatment with active vitamin D ≥ 1 µg/day
Ionized plasma calcium between 1.15-1.25 mmol/L
Disqualifiers
Estimated glomerular filtration rate (eGFR) < 30 ml/min/1.73 m3
Active cancer or former (except thyroid and basal cell skin) cancer treatment < 1 year ago
Pregnancy, pregnancy plans, or breastfeeding < 1 year ago
Abnormal arterial pressure at time of screening defined as symptomatic hypotension or systolic blood pressure < 100 mmHg
Trial design
Treatments tested in this trial
- Indapamide 1.5 MG SR
- Placebo
Treatment groups
24 Participants
are divided into 2 treatment groupsSponsors and collaborators
Lars Rejnmark
Lead sponsor
University of Aarhus
Sponsor institution
Source ClinicalTrials.gov