Use of Letrozole for Ectopic Pregnancy
ConditionEctopic Pregnancy
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18+
SponsorHospital de Clinicas de Porto Alegre
About this trial
A randomized clinical trial using oral letrozole 10mg/day for 7 days, for treating early cases of ectopic pregnancy, compared to intramuscular methotrexate
Eligibility criteria
Qualifiers
18 years or older
Diagnosis of ectopic pregnancy
Desire for reproduction
Ease of return
Disqualifiers
Presence of a significant amount of free fluid in the pelvis (as assessed by the ultrasound technician)
Allergy to methotrexate or letrozole
A reduction in β-hCG ≥ 50% in 2 measurements with 48 hours between them or
Abnormal liver function test (Alanine transaminase (ALT) ≥ 2 times the upper limit of normal)
Trial design
Treatments tested in this trial
- Letrozole tablets
- Methotrexate Sodium
Treatment groups
130 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov