This study will establish a clinical cohort of children with congenital diarrhea and enteropathy (CODE), mine biomarkers of CODE through multi-omics technology and construct a clinical risk prediction model.
Patients with chronic diarrhea lasting greater than 2 months or greater than 1 month in patients younger than 2 months of age
Patients with consent from parents or legal guardians
Chronic diarrhea caused by specific infections, i.e. CMV, Clostridioides difficile
Chronic diarrhea with necrotizing enterocolitis, short bowel syndrome
Functional diarrhea
Patients with poor compliance