Phenotyping Resting and Exertional Right Ventricular Dysfunction Among Patients With Chronic Obstructive Pulmonary Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40+
SponsorUniversity of Colorado, Denver

About this trial

This study plans to learn about heart function among individuals with chronic obstructive pulmonary disease (COPD). In particular, the investigators want to understand the different patterns of right ventricular response during rest and moderate- vs high-intensity exercise. By identifying patterns of right ventricular dysfunction, this study will help identify better treatments for patients with COPD in the future.

Eligibility criteria

Qualifiers

COPD (determined by ratio of forced expiratory volume in 1 second to forced vital capacity [FEV1/FVC] <0.7)

Age >= 40 years

Disqualifiers

Exacerbation of COPD in the 3 months prior to enrollment

Change in COPD therapy in the 3 weeks prior to enrollment

Requirement of >6 LPM supplemental oxygen at rest

Requirement of >10 LPM supplemental oxygen with exertion

Trial design

Treatments tested in this trial

  • Exercise

Treatment groups

60 Participants
are divided into 1 treatment group

Sponsors and collaborators