Phosphatidylethanol and Other Ethanol Consumption Markers
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21+
SponsorThe University of Texas Health Science Center at San Antonio
About this trial
This study is intended to help the investigators understand how a biomarker found in the blood may be used to better identify the quantity and different patterns of alcohol use.
The investigators hope that the results of this study will help identify the uses of alcohol-use markers in the blood in future alcohol prevention and treatment programs. It is hoped that the information learned from this study will benefit other people in the future.
The study participants will come into the lab and will (1) consume alcohol in the lab designed to produce a peak blood alcohol concentration of 0.06% and have blood collected over 6 hours followed by abstinence for 10 days to give a small blood sample 4 times and (2) to give a small amount of blood 5 times within 28 days (naturalistic drinking) and provide answers about alcohol use.
Eligibility criteria
Qualifiers
are ≥ 21 years old;
are height and weight proportionate (body mass index 18-30); and
report drinking on > 1 days in the last month, with at least one day equal to at least achieving ~0.06% BAC.
Disqualifiers
have significant current or predicted alcohol withdrawal symptoms (CIWA-AR scores ≥ 10);
are currently in alcohol treatment;
have substance use disorder (except nicotine, and/or caffeine);
have a medical condition that would contraindicate participation (a positive urine pregnancy test, self-reported scheduled surgery or liver disease);
Trial design
Treatments tested in this trial
- Alcohol (Ethanol)
Treatment groups
80 Participants
are divided into 1 treatment groupSponsors and collaborators
The University of Texas Health Science Center at San Antonio
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Collaborator
Source ClinicalTrials.gov