Photodynamic Therapy as an Adjunct in Periodontal Treatment
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorUniversidad Catolica Santiago de Guayaquil
About this trial
This study aims to evaluate the clinical effectiveness of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of periodontitis. A split-mouth design will be used, in which one hemiarch receives conventional SRP and the contralateral hemiarch receives SRP combined with aPDT. Clinical periodontal parameters, including probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BOP), plaque index (PI), and gingival index (GI), will be assessed at baseline and 30 days after treatment. The study seeks to determine whether adjunctive aPDT improves periodontal outcomes compared with conventional non-surgical periodontal therapy alone.
Eligibility criteria
Qualifiers
Adults aged 18 to 65 years.
Diagnosis of Stage I, II, III, or IV periodontitis according to the 2018 World Workshop Classification.
Presence of at least two hemiarches with periodontal pockets ≥5 mm suitable for a split-mouth design.
Systemically healthy individuals.
Disqualifiers
Uncontrolled systemic diseases that may affect healing or immune response.
Use of antibiotics, corticosteroids, or immunosuppressive medications within the previous 3 months.
Active smokers consuming more than 10 cigarettes per day.
Pregnant or breastfeeding women.
Trial design
Treatments tested in this trial
- Scaling and Root Planing
- Antimicrobial Photodynamic Therapy
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov