This clinical trial studies whether physiatry-led cancer prehabilitation can be used during systemic treatment before surgery (neoadjuvant systemic treatment \[NST\]) to improve function in stage III-IVA gynecologic cancer patients. Treatment of gynecologic cancers presents significant challenges to physical and mental health and patients often experience many challenges following treatment including sleep disturbance, extreme tiredness, sexual dysfunction, and bowel and urinary problems. Patients who have low functioning prior to surgery often have worse outcomes following surgery; however, services to support functional shortages often start after surgery. Physiatry-led cancer prehabilitation is a strategy aimed at reducing post-treatment functional challenges by improving physical and mental function before treatment. It involves physiatry, which is a medical specialty focused on function. Physiatry involvement in prehabilitation allows for the evaluation and management of co-existing conditions, medical supervision, and the coordination of complex plans involving multiple teams. Using physiatry-led cancer prehabilitation during NST may be an effective way to improve function in stage III-IVA gynecologic cancer patients.
PATIENT: Documented informed consent of the participant
PATIENT: Willingness to comply with a physiatry consultation, start a tailored training program, and follow-up assessments
PATIENT: Age: ≥ 18 years
PATIENT: Able to read and write in English
PATIENT: Current or planned cancer treatment for a second cancer
PATIENT: Clinically significant uncontrolled illness limiting participation with the research intervention and assessments
PATIENT: Stage IVB cancer with distant metastases
PATIENT: Other active malignancy
City of Hope Medical Center
Lead sponsor
National Cancer Institute (NCI)
Collaborator