Physical Activity and Insulin Sensitivity Dynamics
ConditionInsulin Sensitivity
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age22-35
SponsorUniversity of Copenhagen
About this trial
The study investigates the role of one single bout of exercise in mediating enhancement of muscle insulin sensitivity following a single bout of exercise. Furthermore, the study is aiming to elucidate the temporal development in insulin signaling, at the early timepoints of insulin stimulation that may be responsible for the enhanced muscle insulin sensitivity.
This will be investigated in young healthy males subjected to a one-legged knee-extensor exercise followed by a hyperinsulinemic-euglycemic clamp, a setup known to enhance muscle insulin sensitivity.
Eligibility criteria
Qualifiers
Healthy individuals (no known diseases)
No use of medication
Non-smokers
Male
Disqualifiers
Women
Failure to meet all inclusion criteria
Physical activity level (e.g., running, cycling, fitness, etc.) exceeding 6 hours per week
Acute illness within 2 weeks prior to the study days
Trial design
Treatments tested in this trial
- One-legged-knee extensor exercise
- Insulin infusion
- Muscle Biopsy Medication: Lidocaine
- Exercise
Treatment groups
8 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov