Physical Fitness and Hot Executive Function in Alzheimer's Risk
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50-70
SponsorNational Taiwan Normal University
About this trial
This 18-month study tracks how physical fitness relates to executive function in older adults, aiming to determine if fitness improvements predict better cognitive performance. Participants complete assessments at baseline and 18 months, including cardiorespiratory fitness (YMCA bike test), muscle strength (chest and leg press tests), and executive function (computer tasks with brain activity recording via EEG). Additional measures include physical activity questionnaires, cognitive screening (MMSE), memory tests (digit span), demographics (age, sex, education), and blood tests for APOE ε4 gene status. No exercise program will be provided, allowing observation of natural fitness-cognition relationships in daily life.
Eligibility criteria
Qualifiers
Age 50-70.
Able to engage in fitness testing.
Normal vision or corrected-to-normal vision.
Disqualifiers
Suffering from cardiopulmonary-related diseases.
Suffering from cognitive, neurological or psychiatric disorders (e.g., dementia, Parkinson's disease, epilepsy, depression, schizophrenia, etc.).
Suffering from infectious diseases (e.g., hepatitis, human immunodeficiency virus or Creutzfeldt-Jakob disease).
Having a history of drug or alcohol abuse.
Trial design
Treatments tested in this trial
- observation alone
Treatment groups
240 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov