Physical Impairments in Premature Ventricular Complex
ConditionPremature Ventricular Complexes
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIzmir Democracy University
About this trial
Premature ventricular complexes may be observed in individuals without underlying disease due to factors such as physical inactivity, advanced age, smoking, male sex, and psychosocial disturbances, and in some cases may result in sudden cardiac death. Therefore, the aim of this study is to investigate respiratory function, respiratory muscle strength, cough strength, handgrip strength, physical activity level, and quality of life in individuals with premature ventricular complexes.
Eligibility criteria
Qualifiers
Aged between 18 and 80 years
Presence of symptomatic premature ventricular complexes resistant to ≥1 antiarrhythmic medication (including β-blockers and calcium channel blockers)
Premature ventricular complex burden ≥10%
Ventricular arrhythmias originating from any focus within the right or left ventricle
Disqualifiers
Left ventricular ejection fraction (LVEF) <45% unless PVC-induced cardiomyopathy is documented (defined as a >15% improvement in LVEF following reduction of PVC burden through pharmacological therapy or ablation)
Progressive decline in LVEF within the last 4 months, regardless of etiology
Severe heart failure classified as New York Heart Association (NYHA) Class ≥III
Ventricular arrhythmias attributed to underlying structural heart disease, known myocardial scar, or myocarditis
Trial design
Treatments tested in this trial
- Physical Evaluations of Patients with Premature Ventricular Complex
- Physical Evaluations of Healthy Individuals
Treatment groups
52 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov