Physical Inactivity and Appetite Regulation
ConditionOverweight
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age40-55
SponsorRigshospitalet, Denmark
About this trial
The goal of this parallel-group, two-arm, assessor-blinded, randomised clinical trial is to investigate the effects of reducing physical activity on food intake and satiety in physically active and healthy males, 40-55 years of age.
The main questions it aims to answer are:
* Does physical inactivity affect GLP-1 stimulated food intake? * Does physical inactivity affect food preferences, satiety and other mechanisms supporting appetite regulation?
Participants will be randomised (1:1) to two weeks of either no intervention (control group) or inactivity. Inactivity will be implemented as cessation of active commuting and all other structured exercise. Furthermore, steps will be reduced to a maximum of 1500 steps/day.
Researchers will compare the inactivity group to the control group to see if physical inactivity impairs appetite regulation.
Eligibility criteria
Qualifiers
Male
Age ≥ 40 years and ≤ 55 years
Body mass index (BMI) > 20 and < 25 kg/m2
Physical activity level should as a minimum include: Active commuting by biking a minimum of 10 km, four days per week or an equivalent amount of other physical activity four days per week.
Disqualifiers
Clinical or biochemical signs of disease
HbA1c > 39 mmol/mol
Unable to allocate the needed time to fulfill the intervention
Language barrier, mental incapacity, unwillingness, or inability to understand and be able to complete the interventions
Trial design
Treatments tested in this trial
- Inactivity
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov