Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD

ConditionCOPD

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-100

SponsorUniversity of Miami

About this trial

This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Able to consent

Age 18 years or older

Diagnosis of COPD

Ability to ambulate without assistance

Disqualifiers

Pregnancy

Being on bedrest

Inability to consent or cooperate with the study

Using of > 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime

Trial design

Design model

Crossover

Treatments tested in this trial

Nasal High Flow Cannula
Device
High flow nasal cannula is a device that provides heated and humidified high flow gases. In-person. Depending on participant's availability, up to 6 times
Nasal Low Flow Cannula
Device
Low flow nasal cannula is a device that provides low flow gases. In-person. Depending on participant's availability, up to 6 times

Treatment groups

45 Participants

are divided into 2 treatment groups

Group A: Nasal High Flow CannulaExperimental treatment 2 interventions

Group B: Nasal Low Flow CannulaActive comparator 2 interventions

Trial outcomes

Primary outcomes

6-minute walk test

The object of the test is to walk as far as possible for six minutes. The subject will walk at a normal pace around a marked course for six minutes. The distance walked in meters over 6 minutes will be measured.

Time frame

30 minutes

Secondary outcomes

Breathing measured by the Borg dyspnea scale

This is a patient self-reported scale to rate the difficulty of breathing. The scale ranges from 0 to 10, where "0" indicated no difficulty breathing, and "10" indicates a maximal breathing difficulty.

Time frame

30 minutes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Miami

Lead sponsor

American Thoracic Society

Collaborator

Source ClinicalTrials.gov

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