A single centre, non-profit, randomised, unblinded pilot study on volume definition for spinal stereotactic body radiation therapy treatment.
Randomization will be 1:1 between two types of SBRT treatment for spinal metastases. The statistical unit will be the individual vertebral metastasis. Multiple metastases will be randomized and evaluated independently.
Patients affected by spinal metastases eligible for SBRT
All histologies are allowed
Oligometastatic disease (maximum 5 metastases) in every setting (oligopersistent, oligorecurrent and oligoprogressive, according to ESTRO consensus)
Metastases treated with ablative intent
More than 2 adjoining vertebrae involved
Palliative intent
2 or more lesions on the target vertebra
Contraindications to MRI