This is a research study investigating elevated homocysteine in the blood of patients with Parkinson's disease who are currently receiving treatment with levodopa. We are evaluating if elevated homocysteine can be corrected using open label B vitamin therapy, as well as the impact of homocysteine levels on cognitive function.
Diagnosis of probable Parkinson's Disease according to Movement Disorders Society criteria.
Currently treated with levodopa at a minimum dose of 300 mg/day
Montreal Cognitive Assessment (MOCA) ≥15
Demonstrated capacity to provide informed consent.
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