The purpose of this study is to develop the safety, feasibility, and tolerability of a personalized transcranial alternating current stimulation (tACS) approach in antenatal depression.
Female aged 18 - 45
Capacity to understand all relevant risks and potential benefits of the study as determined by study staff (provision of informed consent)
Stated willingness to comply with all study procedures and availability for the duration of the study
Low suicide risk (defined for this study as no active suicidal ideation in the past month and no suicide attempts, preparatory actions, or significant non-suicidal self-harm in the previous 2 years). Risk will be assessed utilizing the C-SSRS screen and triage version with further exploration of positive responses.
DSM-5 diagnosis of severe alcohol use disorder (AUD) within the last 12 months, as evidenced by the DIAMOND
DSM-5 diagnosis of moderate to severe substance use disorder (excluding tobacco) within the last 12 months, as evidenced by the DIAMOND
Lifetime history of bipolar disorder, as evidenced by DIAMOND
Schizophrenia spectrum and other psychotic disorders, as evidenced by DIAMOND
University of North Carolina, Chapel Hill
Lead sponsor
Brain & Behavior Research Foundation
Collaborator
Michigan State University
Collaborator