Pioneering Advancements in Cardiocerebrovascular Interactions in the Asia pacFIC - Patent Foramen Ovale Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorNational University Hospital, Singapore

About this trial

A registry of patients from the Asia-Pacific region with PFO and ischemic stroke, designed to study the characteristics, investigations, treatment and outcomes using real-world data.

Eligibility criteria

Qualifiers

Subject has experienced acute ischemic stroke or transient ischemic attack

Subject is screened with presence of PFO (right-to-left shunt) on appropriate cardiac imaging (transthoracic echocardiography and/or transesophageal echocardiography) or transcranial Doppler bubble study

Age ≥18 years

Disqualifiers

Stroke mimics, haemorrhagic stroke or cerebral venous thrombosis

Subjects with less than 3 months of follow up

Trial design

Treatments tested in this trial

  • PFO closure using approved PFO closure devices, Surgical PFO closure
  • Medical management

Treatment groups

1,000 Participants
are divided into 1 treatment group