Health Trials

Pistachio Intake and Nutrition-Related Outcomes in Individuals on GLP-1 Therapy

ConditionsDietary ChangeObesity & OverweightFood Acceptance
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorIan J. Neeland, MD

About this trial

In this study will look at how eating pistachios every day might affect participants weight, how healthy their diet is, and how they feel when eating. Investigators want to see if adding pistachios to meals for 12 weeks helps participants feel fuller, have more energy, and improve body composition. The study will include adults who have been taking GLP-1 medicines like semaglutide or tirzepatide for at least three months. Investigators also want to see if eating pistachios improves overall diet quality and health markers like tiredness and certain levels in blood.

Eligibility criteria

Qualifiers

Individuals with a BMI ≥30 kg/m2 or with a BMI ≥27 kg/m2 with at least one weight-related comorbidity who have been continuously using semaglutide or tirzepatide for three months for a clinical indication and remain on the therapy at the time of enrollment

Disqualifiers

No use or contraindication to use of a GLP-1 RA

Known allergy to nuts

Pregnant or breastfeeding

Incarcerated

Trial design

Treatments tested in this trial

  • Pistachios
  • Dual-energy X-ray absorptiometry (DEXA) scans

Treatment groups

108 Participants
are divided into 2 treatment groups

Locations

1

Map coordinates are unavailable for these locations. Locations are shown below instead.

University Hospitals Cleveland Medical CenterRecruiting44106, Clevland, OhioUnited StatesUnited States

Sponsors and collaborators

Ian J. Neeland, MD

Lead sponsor

University Hospitals Cleveland Medical Center

Sponsor institution

Source ClinicalTrials.gov