About this trial
The goal of this clinical trial is to evaluate the effect of a plant-based diet (PBD) intervention in adults with Rheumatoid Arthritis (RA) on disease activity.
The investigators hypothesize that if patients with RA follow a 100% PBD over a 16-week period it will lead to improvements in:
\- Disease activity (measured by DAS28), including reduction in symptoms and overall improvements in health-related quality of life.
The effects of the PBD will be compared to a habitual diet, that includes no dietary changes.
Participants in the intervention group will:
* Receive weekly delivery of food boxes which include plant-based food items * Receive a daily multivitamin supplement * Receive continuous dietetic guidance * Participate in a practical cooking class to get an introduction to a PBD * Participate in three online supervisions throughout the intervention period
Participants in the control group will follow the same plan for the project visits at the hospital but will be restricted to continue their habitual diet. Thus, not performing any dietary changes.
Eligibility criteria
Qualifiers
Age ≥18 years
DAS28 score ≤3.2, and without swollen joints
RA diagnosis of minimum one year
Stable pharmacological treatment for at least four months and with no planned change in treatment within eight weeks
Disqualifiers
Smokers
Diabetes mellitus
Pregnancy / planned pregnancy
Prednisolone treatment
Trial design
Treatments tested in this trial
- Plant-based diet
Treatment groups
Sponsors and collaborators
Center for Clinical Research and Prevention
Lead sponsor
Glostrup University Hospital, Copenhagen
Collaborator